“phosphorylated pathway― of serine biosynthesis from carbo hydrate intermediates (5). Serine dehydratase is the primary enzyme of serine catabolism. Feeding of a low-protein diet to adult Sprague-Dawley rats

Two enzymes of serine metabolism, 3-P-glycerate dehydro genase and L-serine dehydratase, were measured in four Morris hepatoma lines and in the corresponding host livers of rats that had been fed normal or low-protein diets. The activities of these enzymes in normal rat liver are altered by changes in dietary protein content. 3-P-glycerate dehydrogenase activity was greater in the tumor lines than in normal rat liver or host livers of rats fed a